Lorraine B Ware Selected Research

Primary Graft Dysfunction

10/2023	MICB Genomic Variant Is Associated with NKG2D-mediated Acute Lung Injury and Death.
1/2021	Risk of primary graft dysfunction following lung transplantation in selected adults with connective tissue disease-associated interstitial lung disease.
12/2019	Adipose tissue quantification and primary graft dysfunction after lung transplantation: The Lung Transplant Body Composition study.
1/2019	Postreperfusion plasma endothelial activation markers are associated with acute kidney injury after lung transplantation.
1/2018	Quantitative Evidence for Revising the Definition of Primary Graft Dysfunction after Lung Transplant.
1/2018	Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury.
11/2017	Targeting resolution of pulmonary edema in primary graft dysfunction after lung transplantation: Is inhaled AP301 the answer?
10/2017	Clinical Risk Factors and Prognostic Model for Primary Graft Dysfunction after Lung Transplantation in Patients with Pulmonary Hypertension.
9/2017	Cell-Free Hemoglobin-mediated Increases in Vascular Permeability. A Novel Mechanism of Primary Graft Dysfunction and a New Therapeutic Target.
1/2017	Primary graft dysfunction: pathophysiology to guide new preventive therapies.

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Lorraine B Ware Research Topics

Disease

78	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 05/2024 - 11/2002
77	Acute Lung Injury 11/2023 - 03/2002
50	Sepsis (Septicemia) 05/2024 - 09/2003
38	Inflammation (Inflammations) 04/2024 - 03/2002
38	Pulmonary Edema 01/2023 - 03/2002
35	Critical Illness (Critically Ill) 05/2024 - 06/2002
29	Lung Injury 01/2024 - 01/2003
28	Primary Graft Dysfunction 10/2023 - 01/2007
18	Edema (Dropsy) 01/2021 - 11/2002
17	Acute Kidney Injury (Acute Renal Failure) 12/2023 - 12/2007
12	Shock 04/2024 - 07/2011
11	Wounds and Injuries (Trauma) 01/2020 - 10/2007
10	Pneumonia (Pneumonitis) 01/2023 - 05/2002
9	Respiratory Insufficiency (Respiratory Failure) 04/2024 - 06/2002
9	Hypoxia (Hypoxemia) 01/2024 - 11/2002
9	Chronic Obstructive Pulmonary Disease (COPD) 03/2022 - 09/2007
8	Lung Diseases (Lung Disease) 01/2022 - 05/2002
7	Hyperoxia 01/2023 - 11/2006
7	Kidney Diseases (Kidney Disease) 01/2021 - 01/2011
6	Delirium 04/2024 - 12/2012
6	Obesity 01/2023 - 09/2010
5	COVID-19 01/2023 - 01/2021
5	Pulmonary Arterial Hypertension 01/2023 - 01/2004
5	Idiopathic Pulmonary Fibrosis 01/2021 - 03/2010
4	Neoplasms (Cancer) 01/2022 - 03/2010
4	Asthma (Bronchial Asthma) 01/2022 - 09/2007
4	Necrosis 01/2021 - 12/2004
4	Infections 01/2018 - 04/2007
3	Hypotension (Low Blood Pressure) 05/2024 - 01/2017
3	Cystic Fibrosis (Mucoviscidosis) 01/2022 - 09/2007
3	Fibrosis (Cirrhosis) 01/2021 - 04/2012
3	Pulmonary Hypertension 10/2017 - 01/2004
2	Coma (Comas) 04/2024 - 01/2016
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 03/2024 - 01/2020

Drug/Important Bio-Agent (IBA)

70	Biomarkers (Surrogate Marker)IBA 04/2024 - 01/2003
24	Proteins (Proteins, Gene)FDA Link 01/2023 - 11/2002
22	Hemoglobins (Hemoglobin)IBA 05/2024 - 03/2013
22	Prostaglandins DIBA 10/2023 - 01/2007
19	Protein CIBA 04/2024 - 09/2003
15	Oxygen (Dioxygen)IBA 07/2023 - 01/2003
12	CytokinesIBA 01/2023 - 08/2007
10	CreatinineIBA 12/2020 - 12/2007
10	Thromboplastin (Tissue Factor)IBA 02/2016 - 08/2006
9	Interleukin-6 (Interleukin 6)IBA 04/2024 - 02/2004
9	von Willebrand FactorIBA 06/2019 - 10/2004
8	Acetaminophen (Paracetamol)FDA LinkGeneric 05/2024 - 03/2013
8	Interleukin-8 (Interleukin 8)IBA 04/2024 - 12/2007
8	SmokeIBA 11/2022 - 01/2011
8	Plasminogen Activator Inhibitor 1IBA 01/2019 - 07/2003
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 10/2007
7	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 06/2019 - 01/2003
7	AntigensIBA 06/2015 - 07/2003
7	FibrinIBA 10/2011 - 09/2005
6	ThrombomodulinIBA 05/2016 - 09/2003
6	Blood Proteins (Serum Proteins)IBA 09/2012 - 05/2004
5	Receptor for Advanced Glycation End ProductsIBA 01/2023 - 05/2006
5	Lipocalin-2IBA 10/2019 - 08/2009
5	Plasminogen Activators (Plasminogen Activator)IBA 01/2016 - 07/2003
5	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 02/2010 - 07/2003
4	Secretory Immunoglobulin A (SIgA)IBA 01/2022 - 08/2011
4	Surface-Active Agents (Surfactants)IBA 01/2022 - 01/2003
4	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2021 - 03/2005
4	Messenger RNA (mRNA)IBA 01/2021 - 11/2002
4	Angiopoietin-2IBA 01/2021 - 09/2010
4	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2021 - 06/2011
4	Oxidants (Oxidizing Agents)IBA 01/2020 - 11/2006
4	HaptoglobinsIBA 01/2020 - 11/2013
4	InterleukinsIBA 06/2019 - 02/2010
3	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2024 - 09/2006
3	Interleukin-10 (Interleukin 10)IBA 04/2024 - 12/2007
3	RNA (Ribonucleic Acid)IBA 03/2024 - 01/2020
3	OzoneIBA 01/2023 - 05/2016
3	Air Pollutants (Pollutants, Air)IBA 01/2023 - 01/2019
3	Therapeutic UsesIBA 01/2023 - 12/2014
3	InflammasomesIBA 11/2022 - 06/2012
3	AlbuminsIBA 09/2021 - 03/2011
3	Nicotine FDA Link 01/2021 - 11/2004
3	Interleukin-12 (IL 12)IBA 01/2021 - 11/2012
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2020 - 02/2007
3	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 01/2018
3	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 06/2019 - 01/2011
3	drotrecogin alfa activated (Xigris)FDA Link 01/2018 - 01/2008
3	Bleomycin (Blenoxane)FDA LinkGeneric 02/2016 - 04/2012
3	Interleukin-18 (Interleukin 18)IBA 03/2015 - 08/2010
2	EnzymesIBA 05/2024 - 06/2009
2	AnticoagulantsIBA 04/2024 - 01/2008
2	Hypnotics and Sedatives (Sedatives)IBA 04/2024 - 01/2021
2	Bicarbonates (Hydrogen Carbonate)IBA 01/2024 - 08/2014
2	Ascorbic Acid (Vitamin C)FDA LinkGeneric 12/2023 - 01/2018

Therapy/Procedure

30	Therapeutics 01/2024 - 03/2005
29	Lung Transplantation 01/2024 - 01/2007
15	Artificial Respiration (Mechanical Ventilation) 01/2024 - 07/2003
14	Mechanical Ventilators (Ventilator) 07/2021 - 10/2002
12	Critical Care (Surgical Intensive Care) 04/2024 - 12/2004
7	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 01/2024 - 02/2010
6	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2023 - 11/2011
6	Transplantation 10/2017 - 11/2002
4	Intraperitoneal Injections 01/2023 - 10/2019
4	Precision Medicine 01/2022 - 01/2020
3	Length of Stay 01/2018 - 04/2009